Isotopically Labeled Compounds
Medchemexpress LLC Arabinose-d | 77583-92-7 | 5 MG
Arabinose-d is a deuterium-labeled Arabinose, an endogenous metabolite. Stable heavy isotopes like hydrogen, carbon, and other elements are incorporated into drug molecules for use as tracers in quantifying during drug development. Deuteration is of interest due to its potential impact on the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Ribitol-3-13C | 488-81-3 | 99.7% | 153.14 | C413CH12O5 | 5 MG
Ribitol-3-13C is a 13C-labeled ribitol provided as a stable isotope reference standard for analytical and metabolic research. It is intended for use as an internal standard or tracer in mass spectrometry and metabolic flux assays, supplied in small quantities suitable for laboratory workflows.
- High isotopic enrichment and 99.7% chemical purity.
- Suitable as an internal standard for GC/MS and LC/MS analyses.
- Useful for metabolic tracing and flux experiments.
- Available in small, precise quantities for laboratory use.
- Stable crystalline form with defined molecular weight for reliable quantitation.
Cambridge Isotope Laboratories 3-EPI-25-HYDROXYVITAMIN D3 UNLABELED 100 UG/ML IN ETHANOL, 1 ML
3-EPI-25-HYDROXYVITAMIN D3 UNLABELED 100 UG/ML IN ETHANOL, 1 ML
Cayman Chemical NItenpyram-d3 500ug
An internal standard for the quantification of nitenpyram by GC- or LC-MS
Medchemexpress LLC Nonanoic acid-d17 | 130348-94-6 | 25 MG
Nonanoic acid-d17 is the deuterium labeled Nonanoic acid. Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. It significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Pristane-d40 | 16416-35-6 | 25 MG
Pristane-d40 is the deuterium labeled Pristane. Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, various marine organisms, and as the most active component of mineral oil. It is a non-antigenic adjuvant and induces MHC class II-restricted, arthritogenic T cells in the rat.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Adamantane-d16 | 30470-60-1 | 5 MG
Adamantane-d16 is the deuterium labeled Adamantane. Adamantane is a polycyclic cage molecule with high symmetry and remarkable properties. It can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and can also serve as an anchor in the lipid bilayer of liposomes. It may be used in research of surface recognition and drug delivery. Deuteration has gained attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs by incorporating stable heavy isotopes into drug molecules for quantitation during the drug development process.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Apexbio Technology LLC Nortriptyline (hydrochloride) 894-71-3 10mM (in 1mL DMSO)
Nortriptyline hydrochloride (CAS 894-71-3) is a dibenzocycloheptene-derived tricyclic antidepressant that inhibits monoamine reuptake transporters It selectively blocks the norepinephrine transporter (NET) with a Ki of 3 4 nM and inhibits the serotonin transporter (SERT) with a Ki of 161 nM thereby increasing synaptic concentrations of these neurotransmitters in the central nervous system In vitro nortriptyline dose-dependently suppresses spontaneous migration and chemotaxis of human polymorphonuclear cells In vivo studies in rodents indicate partial blockade of noradrenaline depletion in nerve terminals at higher doses Nortriptyline is frequently employed in research on monoaminergic neurotransmission and antidepressant pharmacology
Cayman Chemical -SItaglIptIn-d4hydrochlo 1mg
An internal standard for the quantification sitagliptin by GC- or LC-MS
Medchemexpress LLC Benzoic acid, 2-(acetyl-2,2,2-d3-oxy)- | 921943-73-9 | 99.8% | 183.18 | 25 MG
Aspirin-d3 is the deuterium labeled Aspirin. Aspirin (Acetylsalicylic acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. It induces apoptosis, inhibits the activation of NF-κB, and also inhibits platelet prostaglandin synthetase, which can prevent coronary artery and cerebrovascular thrombosis.
- Deuterium-labeled compound with stable heavy isotopes
- Can affect pharmacokinetic and metabolic profiles of drugs
- Used as a tracer and internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Orally active, potent, and irreversible inhibitor of cyclooxygenase COX-1 and COX-2
- Induces apoptosis, inhibits NF-κB activation, and platelet prostaglandin synthetase
Cambridge Isotope Laboratories LABELED CARNITINE STANDARDS SET B, 10 VIALS
LABELED CARNITINE STANDARDS SET B, 10 VIALS
![Medchemexpress LLC L-leucine-2,3,3,4,5,5,5,5',5',5'-d10, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- | 1190594-22-9 | None | 98.9% | 363.47 | C21H13D10NO4 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000213247.png-250.jpg)
Medchemexpress LLC L-leucine-2,3,3,4,5,5,5,5',5',5'-d10, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- | 1190594-22-9 | None | 98.9% | 363.47 | C21H13D10NO4 | 25 MG
Fmoc-leucine-d10 is a deuterium-labeled, Fmoc-protected L-leucine supplied as a research reagent for isotopic labeling, peptide synthesis, and analytical standards. It is offered at high chemical purity for use in mass spectrometry, synthetic chemistry, and biological studies where isotopic tracers are required.
- Deuterium-labeled (d10) Fmoc-protected amino acid.
- High purity: 98.9%.
- Molecular weight 363.47 and formula C21H13D10NO4.
- Available in small research quantities such as 25 MG.
- Suitable as an MS internal standard and isotopic tracer.
- Reported to modulate PPARγ activity in biological assays.
Cayman Chemical LeflunomIde-d4 500ug
An internal standard for the quantification of leflunomide by GC- or LC-MS